The research interests of Koç University Transplant Immunology Research Center of Excellence TIREX Director Prof. Caner Süsal, who received many scientific awards and held several leadership positions in the fields of organ transplantation and transplantation immunology, cover all aspects of organ transplantation and transplantation immunology, including transplantation of highly immunized patients, transplantation of organs from expanded criteria donors, induction of unresponsiveness to allografts, pre- and post-transplant risk estimation, matching of organ donor/recipient pairs at epitope level, and identification of biomarkers that reflect the balance between the effector and regulatory components of the alloimmune response.